WOO®
Kollagen Forest fruit

Collagen is a dietary supplement. The European Food Safety Authority (EFSA) does not issue a health claim for collagen. Therefore it follows that statements and suggestions about collagen are very sensitive. We rely therefore on independent study results.

Source: https://de.wikipedia.org/w/index.php?title=Kollagen-Hydrolysat&oldid=184817906

Several clinical studies consistently have shown a strong effect on skin regeneration, skin hydration and skin elasticity of collagen hydrolysate with short chain collagen oligopeptides. The depth of wrinkles could be significantly and sustainably reduced. The skin was improved visibly and sustainably. The age-related decline in the synthesis of collagen and other components of the extracellular matrix of the skin could be positively influenced. These mechanisms are also discussed as the basis for the positive effects of collagen hydrolysate on individuals with cellulitis. For example, a double-blind, placebo-controlled clinical study in 105 women showed that daily intake of collagen hydrolysate over a 6-month period significantly improves skin density and skin texture and reduces cellulite-typical dents.

Proksch et al. (2014) Skin Pharmacol Physiol; 27:47-55
Hunter D. (2011): Pharmacologic therapy for osteoarthritis – the era of disease modification. In: Nat Rev Rheumatol 54: 47-49.
Henrotin Y. et al. (2011): Nutraceuticals: do they represent a new era in the management of osteoarthritis? – a narrative review from the lessons taken with five products. In: Osteoarthritis Cartilage 19 (1): 1-21.
Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, Oesser, S. (2014): Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis; In: Skin Pharmacol Physiol 2014; 27:113–119
Schunck, M., Zague, V., Oesser, S., Proksch, E. (2015): Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. In: J Med Food 00 (0) 2015, 1–9. doi:10.1089/jmf.2015.0022

Source: https://de.wikipedia.org/w/index.php?title=Kollagen-Hydrolysat&oldid=184817906

For more than two decades scientists have been researching the effect of collagen hydrolyzate on articular cartilage.

Initial studies by the University of Kiel have suggested that cartilage formation can be favoured by the administration of collagen hydrolyzate and show that the radioactively labeled short-chain collagen peptides can actually accumulate in the joints and stimulate cartilage formation there. Thus, for the first time both the very good bioavailability and the bioactivity of certain collagen hydrolysates with short-chain collagen peptides could be detected

But only in 2011 could the research group of McAlindon et al. in a clinically controlled gold standard study using objective parameters such as MRI (Magnetic Resonance Imaging using the newly developed dGEMRIC technique), prove that a collagen hydrolyzate with short-chain collagen peptides not only inhibits articular cartilage degeneration but also stimulates its regeneration.

Oesser S. et al. (1999): Oral administration of 14 C labeled gelatin hydrolysate leads to accumulation of radioactivity in cartilage of mice (C57/BL). In: J Nutr 129: 1891-1895.
Oesser S. et al. (2003): Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen. Cell Tiss Res 311: 393-399.
McAlindon T.E. et al. (2011): Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial. In: Osteoarthritis Cartilage 19 (4): 399-405.
Moskowitz RW (2000): Role of collagen hydrolysate in bone and joint disease. In: Semin Arthritis Rheum 30: 87-99.

• Magnesium and protein contribute to the maintenance of normal bones.
• Protein contributes to the maintenance of muscle mass.
• Magnesium contributes to normal muscle functions.
• Magnesium contributes to normal protein synthesis.

Vitamin C contributes to normal collagen formation for normal blood vessel function, bone and cartilage functions.

• Magnesium, vitamin B6 and vitamin C contribute to a normal energy metabolism.
• Vitamin B6 contributes to a normal homocysteine metabolism
• Vitamin B6 contributes to normal protein and glycogen metabolism.
• Vitamin B6 contributes to normal cysteine synthesis.
• Magnesium, Vitamin B6 and Vitamin C help reduce fatigue and tiredness.
• Magnesium, vitamin B6 and vitamin C contribute to a normal mental function.

Collagen hydrolysate (84.5%), dextrose, acidifier citric acid, flavouring, magnesium salts of citric acid, L-ascorbic acid, N-acetyl-L-cysteine, sweetener stevioyl glycoside, colouring agent beetroot powder, L-tryptophan, pyridoxine hydrochloride, colouring agent beta-carotene